Successful Pregnancy by Improving Sperm Parameters Based on Iranian Traditional Medicine (Persian Medicine) – a Case Report

Document Type : Case reports or series

Authors

1 Assistant Professor, Research Institute for Islamic and Complementary Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran

2 Department of Traditional Medicine,School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran,Iran.

Abstract

Background: Treatment of male infertility is an issue in all societies. Abnormalities of sperm parameters constitute almost half of the causes of infertility worldwide. The cause of the disorder is unclear in many cases, and thus male idiopathic infertility is diagnosed for the patient. Medications are usually not very successful in these patients. Therefore, many patients have to resort to assisted reproductive technologies at a high cost. Hence, finding effective therapies for clinicians and researchers is of great value.
Case Presentation: The patient is a 34-year-old man with a two-year history of idiopathic infertility. He had used various drugs to improve sperm parameters, none of which was successful. Finally, after 3 months of using an Iranian Traditional Medicine (ITM) product, lobub morakab, the patient had a significant improvement in spermogram parameters and the patient’s spouse became pregnant.
Conclusion: ITM offers various treatments and strategies for infertility, one of which is the drug reported in this article. Integrating the rich resources of ITM with assisted reproductive technology can bear good results for patients.

Keywords


1. Gurunath S. et al, Defining infertility: a systematic review of prevalence studies. Human reproduction update, 2011, 17: 575-88.
2. Behjati Ardekani Z, Akhondi MM, Kamali K, Fazli Khalaf Z, Eskandari S, Ghorbani B. Mental health status of  patients attending avicenna infertility clinic. J Reprod Infertil 2010 Dec;11(4(45)):319-24
3. Andreas Jungwirtha, Aleksander Giwercmanb. European Association of Urology Guidelines on Male Infertility: The 2012 Update. European Urology, Volume 62, Issue 2, August 2012, Pages 324-332.
4. Tournaye HJCohlen BJ. Management of male-factor infertility. Best Pract Res Clin Obstet Gynecol. 2012 Dec;26(6):769-75. doi: 10.1016/j.bpobgyn.2012.05.005. Epub 2012 Jun 16.
5. Aitken RJ, Oxidative stress, DNA damage and Y chromosome. Reproduction 2001; 122:497-506.
6. Eslamian G, Amirjannati N, Sadeghi MR, Rashidkhani S, Hooshangi A, Hekmatdoost A. The effects of combined supplementation of docosahexaenoic acid and vitamin E on fatty acid changes in sperm membrane in asthenozoospermic men. Iran J Nutr Sci Food Technol 2013; 8(1):33-7.
 7. Sinclair s.male infertility:nutritional and environmental considerationals. Altern Med Rev. 2000; 5(1):28-38.
 8. Vandekerckhove P et al. Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia, Cochrane Database Syst Rev. 2007 Jul 18; (4):CD000150.
 9. Speroff L, A.Fritz M. Clinical Gynecologic Endocrinology and Infertility. Philadelphia: Williams and Wilkins. (2005).
10. World Health Organization. WHO Laboratory Manual for the Analysis of Human Semen and Sperm Cervical Mucus Interaction. 5th ed. Cambridge, UK: Cambridge University Press; 2010.
11. Jorjani SI, Zakhire K. Qom: Rehabilitation Institute of Natural Medicine; 2013.
12. Razi Z. Alhavy Altb. Correction by Heisam Taeemi, Dar Al Ehya Al Arabi; 2002.
13. M Tansaz, S Adhami, R Mokaberinejad, B Namavar Jahromi, F Atarzadeh, An overview of the causes and symptoms of male infertility from the perspective of traditional persian medicine. The Iranian Journal of Obstetrics, Gynecology and Infertility 18 (182), 11-17
14. Ibn Sina H. Al-Qanun fi al-Tibb. Beirut, Lebanon: Dar al-kotobalelmiyah; 1991.
15. Al-Razi AMZ. Resale Bahyh. Tehran: Institute of History of Medicine; 2009. (Persian).
16. Mahroozade S, Sohrabvand F, Bios S, et al. Male infertility in Iranian traditional medicine, causes, treatment and compares it with modern medicine. Iran J Obstet Gynecol Infertil. 2016; 18:1–11.
17. El-Taieb MA, Herwig R, Nada EA, Greilberger J, Marberger M. Oxidative stress and epididymal sperm transport, motility and morphological defects. Eur J Obstet Gynecol Reprod Biol. 2009;144:199-203.
18. Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, eds. Modern Nutrition in Health and Disease. 10th ed. Philadelphia PA: Lippincott Williams & Wilkins; 2006.
19. Zhou X, Liu F, Zhai S. Effect of L-carnitine in nutrition treatment for male infertility: a systematic review. Asia Pac J Clin Nutr. 2007;16:383-389.
20. Balercia G, Mancini A, Paggi F, et al. Coenzyme Q10 and male infertility. J Endocrinol Invest. 2009;32:626-632.
21. Schlegel P. Supplement to enhance male fertility. Biennial Rev Infertil. 2013;3-7.
22. Heydar M, Hassan S. Scientific Basis of Health and Diet Food. Tehran, Iran: Islamic Culture Publications Office; 2007.
23. Sohrabvand F, Mahroozade S, Bioos S.  Improvement in Sperm Parameters with Traditional Iranian Remedy: A Case Report. Journal of Evidence-Based Complementary & Alternative Medicine.2016.
24. Soodabeh Bioos1, Esmail Nazem, Farnaz Sohrabvand, Hamid Sohanaki, Fatemeh Nejatbakhsh. A Traditional Iranian Medicine (Majoon-e Loboob) for Idiopathic Male Infertility: A Case Series. Traditional and Integrative Medicine 2016. 1(1):47-51.
25. Sohrabvand F, Mahroozade S, Bioos S, Nazari SM, Dabaghian FH. Improvement in Sperm Parameters with Traditional Iranian Remedy: A Case Report. Journal of evidence-based complementary & alternative medicine. 2017 Apr; 22(2):223-6.