Colchicum luteum Baker (Suranjan Talkh): Current Perspective on Therapeutic Properties

Document Type : Review

Authors

1 Department of Ilaj bit Tadbeer, Sanskriti Unani Medical College Chhata, Mathura, UP, India

2 Department of Ilaj bit Tadbeer, National Institute of Unani Medicine, Kottigepalya, Magadi Main Road, Bengaluru, India

3 Department of Tahaffuzi wa Samaji tib, Sanskriti Unani Medical College Chhata, Mathura UP, India

Abstract

Suranjan(Colchicum luteum baker) is one of the oldest drugs known to mankind. Suranjan Talkh is considered as the first line drug in the management of arthritis (WajaʻulMafaṣil). Colchicum luteum is one of the rarest and hence most expensive medicinal plants. This drug has a momentous position in the Unani system of medicine and text. It is an active part of many Unani formulations due to the presence of the alkaloid colchicine, which is claimed to be effective in arthritis, gout, rheumatism, and used as a carminative, laxative, and aphrodisiac. It is also applied externally to relieve inflammation and pain. The main objective of this review paper is to elucidate the taxonomic, pharmacognostic, and physicochemical behaviour of Colchicum luteum. The present paper is also an attempt to bring this effective drug to limelight by describing its palliative, therapeutic and other uses.

Graphical Abstract

Colchicum luteum Baker (Suranjan Talkh): Current Perspective on Therapeutic Properties

Keywords


Kabīr al-Dīn ḤM. Mākhzan al-Mufradāt. New Delhi: IdaraKiatabusshifa; 2002:270.
Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. Vol- I&II. 47th edition. Pune. NiraliPrakashan; 2012;1.10.
Siddiqui MZ, Ahmad G, Amin KM, Akhtar S, Rehman A. HPLC profiling conclusively distinguished two important Unani drugs, namely, SuranjanShirin (Colchicum autumnale) and SuranjanTalkh (Colchicum luteum). Indian Journal of Traditional Knowledge (IJTK). 2019 Dec 27;19(1):170-3.
Ghanī N. Khaza’inal-Adwia. New Delhi: IdaraKitabusShifa; 2010: 206-207.
Shyambhavee, Bahera BK. Strategy on Remedial use of Colchicine and its Derivatives: A Review. Journal of Pharmacology & Clinical Toxicology.2017;5(7):1098.
Nair V, Singh S, Gupta YK. Evaluation of the disease modifying activity of Colchicum luteum Baker in experimental arthritis. Journal of ethnopharmacology. 27 Jan 2011;133(2):303-7.
Akhtar H, Siddiqi M, Ali D, Waseem M. Suranjan (Colchicum luteum Baker)–An Old Medicinal Plant. Journal of Advanced Research in Biochemistry and Pharmacology. 2018 Sep 7;1(1&2):42-5.
Parajapati ND, Kumar U. Agro’s Dictionary of Medicinal Plants. Jodhpur. Abrobios. 2005:30.
Nadkarni KM. Indian MetricaMedica. Vol.1. Bombay. PopularPrakashan. 2009:119-120.
Saxena RB. Dorothy hybrid of colchicum luteum Baker. Indo-American journal of pharmaceutical sciences.1 Jul 2017;4(7):1918-23.
Ahmed SN, Ahmad M, Shinwari ZK, Shinwari SH. Taxonomic, pharmacognostic and physicochemical authentication of colchicum luteum Baker (SuranjanTalkh) from its commercial adulterant. Pakistan Journal of Botany. 1 Oct 2016;48(5):2039-45.
Ahmad B, Khan H, Bashir S, Nisar M, Hassan M. Inhibition activities of Colchicum luteum Baker on lipoxygenase and other enzymes. Journal of enzyme inhibition and medicinal chemistry. 1 Jan 2006;21(4):449-52.
Anonymous. Reviews on Indian Medicinal Plants. Indian Council for Medical Research, New Delhi,2008;Vol 7, 340-341
Siddiqui MZ, Akhtar S. SuranjanTalkh (Colchicum luteum): A review of an anti-arthritic Unani drug.International Journal of Research and Analytical Reviews. 2019 Jan-March;6(1):328-332.
Khan H, Tariq SA, Khan MA. Biological and phytochemical studies on corms of Colchicum luteum Baker. Journal of Medicinal Plants Research. 30 Dec 2011;5(32):7031-5.
Khare CP, Indian medicinal plants. New Delhi. Springer publishers; 2007: 56-57.
Choopani R, Ghourchian A, Hajimehdipoor H, Kamalinejad M. Scientific evaluation of pharmacological treatment of osteoarthritis in the Canon of medicine. Journal of evidence-based complementary & alternative medicine. Jul 2016;21(3):228-34.
Ansari MY. Munafe-ul-Mufradat. New Delhi. Ejaz Publication; 2012: 376-377.
Kabīr al-Dīn HM. BustanulMufradat. New Delhi: IdaraKitabusShifa; 2002: 359.
Javed M, Khan JA, Siddiqui MM. Effect of Colchicum luteum Baker in the management of rheumatoid arthritis. Indian Journal of Traditional Knowledge. Oct 2005;4(4):421-423.
Anonymous. National Formulary Of Unani Medicine. Part 2, Vol. 1. New Delhi: CCRUM;2007.17.